KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSHB
All Species:
16.67
Human Site:
Y79
Identified Species:
45.83
UniProt:
P01222
Number Species:
8
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P01222
NP_000540.2
138
15609
Y79
C
T
Y
R
D
F
I
Y
R
T
V
E
I
P
G
Chimpanzee
Pan troglodytes
Q2Q1P2
141
15315
V82
V
V
C
T
Y
R
D
V
R
F
E
S
I
R
L
Rhesus Macaque
Macaca mulatta
XP_001111873
138
15545
Y79
C
T
Y
R
D
F
I
Y
R
T
V
E
I
P
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P12656
138
15354
Y79
C
T
Y
R
D
F
I
Y
R
T
V
E
I
P
G
Rat
Rattus norvegicus
P04652
138
15486
Y79
C
T
Y
R
D
F
T
Y
R
T
V
E
I
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506129
129
14437
V71
K
Y
A
L
S
Q
R
V
C
T
Y
D
D
L
I
Chicken
Gallus gallus
O57340
134
15046
E76
Q
N
V
C
T
Y
K
E
M
F
Y
Q
T
A
L
Frog
Xenopus laevis
NP_001084494
134
15104
Y76
C
T
Y
T
D
I
T
Y
E
T
V
K
L
P
G
Zebra Danio
Brachydanio rerio
NP_852471
148
16808
C86
R
T
A
V
L
P
G
C
P
S
H
A
D
P
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.4
98.5
N.A.
N.A.
85.5
85.5
N.A.
70.2
66.6
36.2
41.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
54.6
100
N.A.
N.A.
92.7
89.8
N.A.
80.4
80.4
55
58.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
N.A.
N.A.
100
93.3
N.A.
6.6
0
60
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
100
N.A.
N.A.
100
93.3
N.A.
13.3
13.3
73.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
23
0
0
0
0
0
0
0
0
12
0
12
0
% A
% Cys:
56
0
12
12
0
0
0
12
12
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
56
0
12
0
0
0
0
12
23
0
0
% D
% Glu:
0
0
0
0
0
0
0
12
12
0
12
45
0
0
0
% E
% Phe:
0
0
0
0
0
45
0
0
0
23
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
56
% G
% His:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
12
% H
% Ile:
0
0
0
0
0
12
34
0
0
0
0
0
56
0
12
% I
% Lys:
12
0
0
0
0
0
12
0
0
0
0
12
0
0
0
% K
% Leu:
0
0
0
12
12
0
0
0
0
0
0
0
12
12
23
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
12
0
0
12
0
0
0
0
67
0
% P
% Gln:
12
0
0
0
0
12
0
0
0
0
0
12
0
0
0
% Q
% Arg:
12
0
0
45
0
12
12
0
56
0
0
0
0
12
0
% R
% Ser:
0
0
0
0
12
0
0
0
0
12
0
12
0
0
0
% S
% Thr:
0
67
0
23
12
0
23
0
0
67
0
0
12
0
0
% T
% Val:
12
12
12
12
0
0
0
23
0
0
56
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
12
56
0
12
12
0
56
0
0
23
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _